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Foxd3 suppresses NFAT-mediated differentiation to maintain self-renewal of embryonic stem cells
Pluripotency-associated transcription factor Foxd3 is required for maintaining pluripotent cells. However, molecular mechanisms underlying its function are largely unknown. Here, we report that Foxd3 suppresses differentiation induced by calcineurin–NFAT signaling to maintain the ESC identity. Mecha...
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| Izdano u: | EMBO Rep |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BlackWell Publishing Ltd
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4264931/ https://ncbi.nlm.nih.gov/pubmed/25378483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201438643 |
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