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Niche-mediated control of human embryonic stem cell self-renewal and differentiation
Complexity in the spatial organization of human embryonic stem cell (hESC) cultures creates heterogeneous microenvironments (niches) that influence hESC fate. This study demonstrates that the rate and trajectory of hESC differentiation can be controlled by engineering hESC niche properties. Niche si...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080799/ https://ncbi.nlm.nih.gov/pubmed/17948051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601896 |
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