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Niche-mediated control of human embryonic stem cell self-renewal and differentiation
Complexity in the spatial organization of human embryonic stem cell (hESC) cultures creates heterogeneous microenvironments (niches) that influence hESC fate. This study demonstrates that the rate and trajectory of hESC differentiation can be controlled by engineering hESC niche properties. Niche si...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080799/ https://ncbi.nlm.nih.gov/pubmed/17948051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601896 |
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