Akt suppresses DLK for maintaining self-renewal of mouse embryonic stem cells

Mouse embryonic stem cells (ES cells) can proliferate indefinitely. To identify potential signals involved in suppression of self-renewal, we previously screened a kinase/phosphatase expression library in ES cells, and observed that inhibition of Dual Leucine zipper-bearing Kinase (DLK) increased re...

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Veröffentlicht in:Cell Cycle
Hauptverfasser: Wu, Cheng-Chung, Wu, Hong-Jin, Wang, Chia-Hui, Lin, Chia-Hua, Hsu, Shu-Ching, Chen, Yi-Rong, Hsiao, Michael, Schuyler, Scott C, Lu, Frank Leigh, Ma, Nianhan, Lu, Jean
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
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Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614864/
https://ncbi.nlm.nih.gov/pubmed/25802931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1014144
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