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Exploiting the kinetic interplay between GPIbα–VWF binding interfaces to regulate hemostasis and thrombosis
Platelet–von Willebrand factor (VWF) interactions must be tightly regulated in order to promote effective hemostasis and prevent occlusive thrombus formation. However, it is unclear what role the inherent properties of the bond formed between the platelet receptor glycoprotein Ibα and the A1 domain...
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| Опубликовано в: : | Blood |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Hematology
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263987/ https://ncbi.nlm.nih.gov/pubmed/25293780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-569392 |
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