The E2 Ubiquitin-conjugating Enzyme UBE2J1 Is Required for Spermiogenesis in Mice

ER-resident proteins destined for degradation are dislocated into the cytosol by components of the ER quality control machinery for proteasomal degradation. Dislocation substrates are ubiquitylated in the cytosol by E2 ubiquitin-conjugating/E3 ligase complexes. UBE2J1 is one of the well-characterize...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Koenig, Paul-Albert, Nicholls, Peter K., Schmidt, Florian I., Hagiwara, Masatoshi, Maruyama, Takeshi, Frydman, Galit H., Watson, Nicki, Page, David C., Ploegh, Hidde L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Molecular Bases of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263858/
https://ncbi.nlm.nih.gov/pubmed/25320092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.604132
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