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Post-transcriptional regulation of glycoprotein quality control in the endoplasmic reticulum is controlled by the E2 Ub-conjugating enzyme UBC6e
Endoplasmic reticulum-associated degradation (ERAD) is essential for protein quality control in the ER, not only when the ER is stressed, but also at steady state. We report a new layer of homeostatic control, in which ERAD activity itself is regulated post-transcriptionally and independently of the...
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| Опубликовано в: : | Mol Cell |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010495/ https://ncbi.nlm.nih.gov/pubmed/27570074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.07.014 |
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