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Formation of α-synuclein Lewy neurite–like aggregates in axons impedes the transport of distinct endosomes
Aggregates of α-synuclein (α-syn) accumulate in neurons in Parkinson's disease and other synucleinopathies. These inclusions predominantly localize to axons even in the early stages of the disease, but their affect on axon function has remained unknown. Previously we established a model in whic...
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| Publicado no: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263445/ https://ncbi.nlm.nih.gov/pubmed/25298402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-02-0741 |
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