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Formation of α-synuclein Lewy neurite–like aggregates in axons impedes the transport of distinct endosomes
Aggregates of α-synuclein (α-syn) accumulate in neurons in Parkinson's disease and other synucleinopathies. These inclusions predominantly localize to axons even in the early stages of the disease, but their affect on axon function has remained unknown. Previously we established a model in whic...
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| izdano v: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Cell Biology
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263445/ https://ncbi.nlm.nih.gov/pubmed/25298402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-02-0741 |
| Oznake: |
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