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Initiation and propagation of α-synuclein aggregation in the nervous system

The two main pathological hallmarks of Parkinson’s disease are loss of dopamine neurons in the substantia nigra pars compacta and proteinaceous amyloid fibrils composed mostly of α-synuclein, called Lewy pathology. Levodopa to enhance dopaminergic transmission remains one of the most effective treat...

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Dades bibliogràfiques
Publicat a:Mol Neurodegener
Autors principals: Hijaz, Baraa A., Volpicelli-Daley, Laura A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060612/
https://ncbi.nlm.nih.gov/pubmed/32143659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00368-6
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