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Initiation and propagation of α-synuclein aggregation in the nervous system

The two main pathological hallmarks of Parkinson’s disease are loss of dopamine neurons in the substantia nigra pars compacta and proteinaceous amyloid fibrils composed mostly of α-synuclein, called Lewy pathology. Levodopa to enhance dopaminergic transmission remains one of the most effective treat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Neurodegener
Main Authors: Hijaz, Baraa A., Volpicelli-Daley, Laura A.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060612/
https://ncbi.nlm.nih.gov/pubmed/32143659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00368-6
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