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EGFR blockade enriches for lung cancer stem-like cells through Notch3-dependent signaling

Mutations in the epidermal growth factor receptor (EGFR) are the most common actionable genetic abnormalities yet discovered in lung cancer. However, targeting these mutations with kinase inhibitors is not curative in advanced disease and has yet to demonstrate an impact on potentially curable, earl...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Res
Päätekijät: Arasada, Rajeswara Rao, Amann, Joseph M., Rahman, Mohammad A, Huppert, Stacey S., Carbone, David P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263272/
https://ncbi.nlm.nih.gov/pubmed/25125655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3724
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