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Targeting EGFR Enriches Stem Cell-Like Properties in Salivary Adenoid Cystic Carcinoma by Activating the Notch1 Pathway

BACKGROUND: Salivary adenoid cystic carcinoma (SACC), a rare cancer arising in the salivary glands, is characterized by high rates of relapse and distant metastasis. Epidermal growth factor receptor (EGFR) has been implicated in SACC carcinogenesis. However, prospective trials of EGFR-targeting ther...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Wang, Yang, Han, Yong, Xu, Shengming, Zhang, Ling, Zhang, Xiangkai, Deng, Jiong, Ye, Weimin, Liu, Shuli
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411275/
https://ncbi.nlm.nih.gov/pubmed/32801899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S253500
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