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Targeting EGFR Enriches Stem Cell-Like Properties in Salivary Adenoid Cystic Carcinoma by Activating the Notch1 Pathway

BACKGROUND: Salivary adenoid cystic carcinoma (SACC), a rare cancer arising in the salivary glands, is characterized by high rates of relapse and distant metastasis. Epidermal growth factor receptor (EGFR) has been implicated in SACC carcinogenesis. However, prospective trials of EGFR-targeting ther...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer Manag Res
Hauptverfasser: Wang, Yang, Han, Yong, Xu, Shengming, Zhang, Ling, Zhang, Xiangkai, Deng, Jiong, Ye, Weimin, Liu, Shuli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411275/
https://ncbi.nlm.nih.gov/pubmed/32801899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S253500
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