Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine Lif

Por Chen, Yulong, Deng, Jiong, Fujimoto, Junya, Kadara, Humam, Men, Taoyan, Lotan, Dafna, Lotan, Reuben
Publicado em 2010

Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion

Por Wu, Yadi, Deng, Jiong, Rychahou, Piotr G., Qiu, Suimin, Evers, B. Mark, Zhou, Binhua P.
Publicado em 2009

Epithelial neoplasia coincides with exacerbated injury and fibrotic response in the lungs of Gprc5a-knockout mice following silica exposure

Por Wang, Xiaofei, Xu, Dongliang, Liao, Yueling, Zhong, Shuangshuang, Song, Hongyong, Sun, Beibei, Zhou, Binhua P., Deng, Jiong, Han, Baohui
Publicado no Oncotarget (2015)

Repression of GPRC5A is associated with activated STAT3, which contributes to tumor progression of head and neck squamous cell carcinoma

Por Liu, Shuli, Ye, Dongxia, Wang, Tong, Guo, Wenzheng, Song, Hongyong, Liao, Yueling, Xu, Dongliang, Zhu, Hanguang, Zhang, Zhiyuan, Deng, Jiong
Publicado no Cancer Cell Int (2017)

High Vimentin Expression Associated with Lymph Node Metastasis and Predicated a Poor Prognosis in Oral Squamous Cell Carcinoma

Por Liu, Shuli, Liu, Liu, Ye, Weimin, Ye, Dongxia, Wang, Tong, Guo, Wenzheng, Liao, Yueling, Xu, Dongliang, Song, Hongyong, Zhang, Ling, Zhu, Hanguang, Deng, Jiong, Zhang, Zhiyuan
Publicado no Sci Rep (2016)

Gprc5a-knockout mouse lung epithelial cells predicts ceruloplasmin, lipocalin 2 and periostin as potential biomarkers at early stages of lung tumorigenesis

Por Sun, Beibei, Guo, Wenzheng, Hu, Song, Yao, Feng, Yu, Keke, Xing, Jie, Wang, Ronghua, Song, Hongyong, Liao, Yueling, Wang, Tong, Jiang, Pengfei, Han, Baohui, Deng, Jiong
Publicado no Oncotarget (2017)

Knockout of the Tumor suppressor gene Gprc5a in mice leads to NF-κB activation in airway epithelium and promotes lung inflammation and tumorigenesis

Por Deng, Jiong, Fujimoto, Junya, Ye, Xiao-Feng, Men, Tao-Yan, Van Pelt, Carolyn S., Chen, Yu-Long, Lin, Xiao-Feng, Kadara, Humam, Tao, Qingguo, Lotan, Dafna, Lotan, Reuben
Publicado no Cancer Prev Res (Phila) (2010)

Gprc5a-deficiency confers susceptibility to endotoxin-induced acute lung injury via NF-κB pathway

Por Liao, Yueling, Song, Hongyong, Xu, Dongliang, Jiao, Huike, Yao, Feng, Liu, Jingyi, Wu, Yadi, Zhong, Shuangshuang, Yin, Huijing, Liu, Shuli, Wang, Xiaofei, Guo, Wenzheng, Sun, Beibei, Han, Baohui, Chin, Y. Eugene, Deng, Jiong
Publicado no Cell Cycle (2015)

EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer

Por Lin, Xiaofeng, Zhong, Shuangshuang, Ye, Xiaofeng, Liao, Yueling, Yao, Feng, Yang, Xiaohua, Sun, Beibei, Zhang, Jie, Li, Qi, Gao, Yong, Wang, Yifan, Liu, Jingyi, Han, Baohui, Chin, Y Eugene, Zhou, Binhua P, Deng, Jiong
Publicado em 2014

Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation

Por Wu, Yadi, Wang, Yu, Lin, Yiwei, Liu, Yajuan, Wang, Yifan, Jia, Jianhang, Singh, Puja, Chi, Young-In, Wang, Chi, Dong, Chenfang, Li, Wei, Tao, Min, Napier, Dana, Shi, Qiuying, Deng, Jiong, Mark Evers, B, Zhou, Binhua P.
Publicado no Nat Commun (2017)

G9a is essential for EMT-mediated metastasis and maintenance of cancer stem cell-like characters in head and neck squamous cell carcinoma

Por Liu, Shuli, Ye, Dongxia, Guo, Wenzheng, Yu, Wenwen, He, Yue, Hu, Jingzhou, Wang, Yanan, Zhang, Ling, Liao, Yueling, Song, Hongyong, Zhong, Shuangshuang, Xu, Dongliang, Yin, Huijing, Sun, Beibei, Wang, Xiaofei, Liu, Jingyi, Wu, Yadi, Zhou, Binhua P., Zhang, Zhiyuan, Deng, Jiong
Publicado no Oncotarget (2015)

Disrupting the Interaction of BRD4 with Di-acetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer

Por Shi, Jian, Wang, Yifan, Zeng, Lei, Wu, Yadi, Deng, Jiong, Zhang, Qiang, Lin, Yiwei, Li, Junlin, Kang, Tiebang, Tao, Min, Rusinova, Elena, Zhang, Guangtao, Wang, Chi, Zhu, Haining, Yao, Jun, Zeng, Yi-Xin, Evers, B. Mark, Zhou, Ming-Ming, Zhou, Binhua P.
Publicado em 2014

MicroRNA-31 negatively regulates peripherally derived regulatory T-cell generation by repressing retinoic acid-inducible protein 3

Por Zhang, Lingyun, Ke, Fang, Liu, Zhaoyuan, Bai, Jing, Liu, Jinlin, Yan, Sha, Xu, Zhenyao, Lou, Fangzhou, Wang, Hong, Zhu, Huiyuan, Sun, Yang, Cai, Wei, Gao, Yuanyuan, Li, Qun, Yu, Xue-Zhong, Qian, Youcun, Hua, Zichun, Deng, Jiong, Li, Qi-Jing, Wang, Honglin
Publicado no Nat Commun (2015)

Autocrine epiregulin activates EGFR pathway for lung metastasis via EMT in salivary adenoid cystic carcinoma

Por Liu, Shuli, Ye, Dongxia, Xu, Dongliang, Liao, Yueling, Zhang, Ling, Liu, Liu, Yu, Wenwen, Wang, Yanan, He, Yue, Hu, Jingzhou, Guo, Wenzheng, Wang, Tong, Sun, Beibei, Song, Hongyong, Yin, Huijing, Liu, Jingyi, Wu, Yadi, Zhu, Hanguang, Zhou, Binhua P., Deng, Jiong, Zhang, Zhiyuan
Publicado no Oncotarget (2016)