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Enhancement of growth and survival and alterations in Bcl-family proteins in β-thalassemic erythroid progenitors by novel short-chain fatty acid derivatives
Accelerated apoptosis of erythroid progenitors is a characteristic of β-thalassemia which presents a significant barrier to definitive therapeutic approaches utilizing induction of endogenous fetal globin gene expression. γ-globin gene expression may not be inducible in, or may not be able to rescue...
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| Veröffentlicht in: | Blood Cells Mol Dis |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260805/ https://ncbi.nlm.nih.gov/pubmed/16099182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2005.06.007 |
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