Erythroid Kruppel-like factor (EKLF) is recruited to the γ-globin gene promoter as a co-activator and is required for γ-globin gene induction by short-chain fatty acid derivatives

OBJECTIVES: The erythroid Kruppel-like factor (EKLF) is an essential transcription factor for β-type globin gene switching, and specifically activates transcription of the adult β-globin gene promoter. We sought to determine if EKLF is also required for activation of the γ-globin gene by short-chain...

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Hauptverfasser: Perrine, Susan P., Mankidy, Rishikesh, Boosalis, Michael S., Bieker, James J., Faller, Douglas V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232177/
https://ncbi.nlm.nih.gov/pubmed/19220418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0609.2009.01234.x
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