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Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation

The antitumor activity of an inhibitor of 26S proteasome bortezomib (Velcade) has been observed in various malignancies, including colon cancer, prostate cancer, breast cancer, and ovarian cancer. Bortezomib has been proposed to stimulate autophagy, but scientific observations did not always support...

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書目詳細資料
發表在:Cell Death Dis
Main Authors: Kao, C, Chao, A, Tsai, C-L, Chuang, W-C, Huang, W-P, Chen, G-C, Lin, C-Y, Wang, T-H, Wang, H-S, Lai, C-H
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260726/
https://ncbi.nlm.nih.gov/pubmed/25375375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.468
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