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Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation
The antitumor activity of an inhibitor of 26S proteasome bortezomib (Velcade) has been observed in various malignancies, including colon cancer, prostate cancer, breast cancer, and ovarian cancer. Bortezomib has been proposed to stimulate autophagy, but scientific observations did not always support...
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| 發表在: | Cell Death Dis |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260726/ https://ncbi.nlm.nih.gov/pubmed/25375375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.468 |
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