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Global structural changes of an ion channel during its gating are followed by ion mobility mass spectrometry

Mechanosensitive ion channels are sensors probing membrane tension in all species; despite their importance and vital role in many cell functions, their gating mechanism remains to be elucidated. Here, we determined the conditions for releasing intact mechanosensitive channel of large conductance (M...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Konijnenberg, Albert, Yilmaz, Duygu, Ingólfsson, Helgi I., Dimitrova, Anna, Marrink, Siewert J., Li, Zhuolun, Vénien-Bryan, Catherine, Sobott, Frank, Koçer, Armağan
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260606/
https://ncbi.nlm.nih.gov/pubmed/25404294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413118111
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