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The activation mode of the mechanosensitive ion channel, MscL, by lysophosphatidylcholine differs from tension-induced gating

One of the best-studied mechanosensitive channels is the mechanosensitive channel of large conductance (MscL). MscL senses tension in the membrane evoked by an osmotic down shock and directly couples it to large conformational changes leading to the opening of the channel. Spectroscopic techniques o...

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Detalhes bibliográficos
Main Authors: Mukherjee, Nobina, Jose, Mac Donald, Birkner, Jan Peter, Walko, Martin, Ingólfsson, Helgi I., Dimitrova, Anna, Arnarez, Clément, Marrink, Siewert J., Koçer, Armağan
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202108/
https://ncbi.nlm.nih.gov/pubmed/24958207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-251579
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