Global structural changes of an ion channel during its gating are followed by ion mobility mass spectrometry

Mechanosensitive ion channels are sensors probing membrane tension in all species; despite their importance and vital role in many cell functions, their gating mechanism remains to be elucidated. Here, we determined the conditions for releasing intact mechanosensitive channel of large conductance (M...

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Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Konijnenberg, Albert, Yilmaz, Duygu, Ingólfsson, Helgi I., Dimitrova, Anna, Marrink, Siewert J., Li, Zhuolun, Vénien-Bryan, Catherine, Sobott, Frank, Koçer, Armağan
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2014
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260606/
https://ncbi.nlm.nih.gov/pubmed/25404294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413118111
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