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Top-down mass spectrometry of intact membrane protein complexes reveals oligomeric state and sequence information in a single experiment
Here we study the intact stoichiometry and top-down fragmentation behavior of three integral membrane proteins which were natively reconstituted into detergent micelles: the mechano-sensitive ion channel of large conductance (MscL), the Kirbac potassium channel and the p7 viroporin from the hepatiti...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4534180/ https://ncbi.nlm.nih.gov/pubmed/25970171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2703 |
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