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Fixed-charge Trimethyl Pyrilium Modification Enables Enhanced Top-down Mass Spectrometry Sequencing of Intact Protein Complexes
Mass spectrometry of intact proteins and protein complexes has the potential to provide a transformative level of information on biological systems, ranging from sequence and post-translational modification analysis to the structures of whole protein assemblies. This ambitious goal requires the effi...
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| Udgivet i: | Anal Chem |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6340295/ https://ncbi.nlm.nih.gov/pubmed/29360341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b04806 |
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