Inhibition of tumor cell proliferation and motility by fibroblasts is both contact and soluble factor dependent

Normal human and murine fibroblasts can inhibit proliferation of tumor cells when cocultured in vitro. The inhibitory capacity varies depending on the donor and the site of origin of the fibroblast. We showed previously that effective inhibition requires formation of a morphologically intact fibrobl...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Alkasalias, Twana, Flaberg, Emilie, Kashuba, Vladimir, Alexeyenko, Andrey, Pavlova, Tatiana, Savchenko, Andrii, Szekely, Laszlo, Klein, George, Guven, Hayrettin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260581/
https://ncbi.nlm.nih.gov/pubmed/25404301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419554111
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