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Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth

BACKGROUND: There is growing evidence that emerging malignancies in solid tissues might be kept under control by physical intercellular contacts with normal fibroblasts. METHODS: Here we characterize transcriptional landscapes of fibroblasts that confronted cancer cells. We studied four pairs of in...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Alexeyenko, Andrey, Alkasalias, Twana, Pavlova, Tatiana, Szekely, Laszlo, Kashuba, Vladimir, Rundqvist, Helene, Wiklund, Peter, Egevad, Lars, Csermely, Peter, Korcsmaros, Tamas, Guven, Hayrettin, Klein, George
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472614/
https://ncbi.nlm.nih.gov/pubmed/26081588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0178-x
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