Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling

Atherosclerotic plaque localization correlates with regions of disturbed flow in which endothelial cells (ECs) align poorly, whereas sustained laminar flow correlates with cell alignment in the direction of flow and resistance to atherosclerosis. We now report that in hypercholesterolemic mice, dele...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Baeyens, Nicolas, Mulligan-Kehoe, Mary Jo, Corti, Federico, Simon, David D., Ross, Tyler D., Rhodes, John M., Wang, Thomas Z., Mejean, Cecile O., Simons, Michael, Humphrey, Jay, Schwartz, Martin A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260558/
https://ncbi.nlm.nih.gov/pubmed/25404299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413725111
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