Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development

The role of fluid shear stress in vasculature development and remodeling is well appreciated. However, the mechanisms regulating these effects remain elusive. We show that abnormal flow sensing in lymphatic endothelial cells (LECs) caused by Sdc4 or Pecam1 deletion in mice results in impaired lympha...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Wang, Yingdi, Baeyens, Nicolas, Corti, Federico, Tanaka, Keiichiro, Fang, Jennifer S., Zhang, Jiasheng, Jin, Yu, Coon, Brian, Hirschi, Karen K., Schwartz, Martin A., Simons, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201046/
https://ncbi.nlm.nih.gov/pubmed/27789626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.140129
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