Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development

The role of fluid shear stress in vasculature development and remodeling is well appreciated. However, the mechanisms regulating these effects remain elusive. We show that abnormal flow sensing in lymphatic endothelial cells (LECs) caused by Sdc4 or Pecam1 deletion in mice results in impaired lympha...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Development
Main Authors: Wang, Yingdi, Baeyens, Nicolas, Corti, Federico, Tanaka, Keiichiro, Fang, Jennifer S., Zhang, Jiasheng, Jin, Yu, Coon, Brian, Hirschi, Karen K., Schwartz, Martin A., Simons, Michael
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201046/
https://ncbi.nlm.nih.gov/pubmed/27789626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.140129
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