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Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development
The role of fluid shear stress in vasculature development and remodeling is well appreciated. However, the mechanisms regulating these effects remain elusive. We show that abnormal flow sensing in lymphatic endothelial cells (LECs) caused by Sdc4 or Pecam1 deletion in mice results in impaired lympha...
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| Publié dans: | Development |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists Ltd
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5201046/ https://ncbi.nlm.nih.gov/pubmed/27789626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.140129 |
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