Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling

Atherosclerotic plaque localization correlates with regions of disturbed flow in which endothelial cells (ECs) align poorly, whereas sustained laminar flow correlates with cell alignment in the direction of flow and resistance to atherosclerosis. We now report that in hypercholesterolemic mice, dele...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Baeyens, Nicolas, Mulligan-Kehoe, Mary Jo, Corti, Federico, Simon, David D., Ross, Tyler D., Rhodes, John M., Wang, Thomas Z., Mejean, Cecile O., Simons, Michael, Humphrey, Jay, Schwartz, Martin A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260558/
https://ncbi.nlm.nih.gov/pubmed/25404299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413725111
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