The Syndecan-4/Protein Kinase Cα Pathway Mediates Prostaglandin E(2)-induced Extracellular Regulated Kinase (ERK) Activation in Endothelial Cells and Angiogenesis in Vivo

Prostaglandin E(2) (PGE(2)) is regarded as the main mediator of inflammatory symptoms. In addition, it also plays an important role in tumor growth and angiogenesis. In this study, we examined the mechanism of PGE(2)-induced angiogenic response. We show that in the absence of proteoglycan syndecan-4...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Corti, Federico, Finetti, Federica, Ziche, Marina, Simons, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2013
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642317/
https://ncbi.nlm.nih.gov/pubmed/23525101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.452383
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