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Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow
It has been known for some time that atherosclerotic lesions preferentially develop in areas exposed to low SS and are characterized by a proinflammatory, apoptotic, and senescent endothelial phenotype. Conversely, areas exposed to high SS are protected from plaque development, but the mechanisms ha...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5642679/ https://ncbi.nlm.nih.gov/pubmed/28973855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702223114 |
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