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Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

It has been known for some time that atherosclerotic lesions preferentially develop in areas exposed to low SS and are characterized by a proinflammatory, apoptotic, and senescent endothelial phenotype. Conversely, areas exposed to high SS are protected from plaque development, but the mechanisms ha...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Vion, Anne-Clemence, Kheloufi, Marouane, Hammoutene, Adel, Poisson, Johanne, Lasselin, Juliette, Devue, Cecile, Pic, Isabelle, Dupont, Nicolas, Busse, Johanna, Stark, Konstantin, Lafaurie-Janvore, Julie, Barakat, Abdul I., Loyer, Xavier, Souyri, Michele, Viollet, Benoit, Julia, Pierre, Tedgui, Alain, Codogno, Patrice, Boulanger, Chantal M., Rautou, Pierre-Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642679/
https://ncbi.nlm.nih.gov/pubmed/28973855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702223114
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