Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

It has been known for some time that atherosclerotic lesions preferentially develop in areas exposed to low SS and are characterized by a proinflammatory, apoptotic, and senescent endothelial phenotype. Conversely, areas exposed to high SS are protected from plaque development, but the mechanisms ha...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Vion, Anne-Clemence, Kheloufi, Marouane, Hammoutene, Adel, Poisson, Johanne, Lasselin, Juliette, Devue, Cecile, Pic, Isabelle, Dupont, Nicolas, Busse, Johanna, Stark, Konstantin, Lafaurie-Janvore, Julie, Barakat, Abdul I., Loyer, Xavier, Souyri, Michele, Viollet, Benoit, Julia, Pierre, Tedgui, Alain, Codogno, Patrice, Boulanger, Chantal M., Rautou, Pierre-Emmanuel
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642679/
https://ncbi.nlm.nih.gov/pubmed/28973855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702223114
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