BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells

Genome maintenance by homologous recombination depends on coordinating many proteins in time and space to assemble at DNA break sites. To understand this process, we followed the mobility of BRCA2, a critical recombination mediator, in live cells at the single-molecule level using both single-partic...

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Bibliografski detalji
Izdano u:J Cell Biol
Glavni autori: Reuter, Marcel, Zelensky, Alex, Smal, Ihor, Meijering, Erik, van Cappellen, Wiggert A., de Gruiter, H. Martijn, van Belle, Gijsbert J., van Royen, Martin E., Houtsmuller, Adriaan B., Essers, Jeroen, Kanaar, Roland, Wyman, Claire
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2014
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259808/
https://ncbi.nlm.nih.gov/pubmed/25488918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201405014
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