BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells

Genome maintenance by homologous recombination depends on coordinating many proteins in time and space to assemble at DNA break sites. To understand this process, we followed the mobility of BRCA2, a critical recombination mediator, in live cells at the single-molecule level using both single-partic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biol
Prif Awduron: Reuter, Marcel, Zelensky, Alex, Smal, Ihor, Meijering, Erik, van Cappellen, Wiggert A., de Gruiter, H. Martijn, van Belle, Gijsbert J., van Royen, Martin E., Houtsmuller, Adriaan B., Essers, Jeroen, Kanaar, Roland, Wyman, Claire
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2014
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259808/
https://ncbi.nlm.nih.gov/pubmed/25488918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201405014
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