Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase

The recombinase RAD51, and its meiosis-specific paralog DMC1 localize at DNA double-strand break (DSB) sites in meiotic prophase. While both proteins are required during meiotic prophase, their spatial organization during meiotic DSB repair is not fully understood. Using super-resolution microscopy...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Slotman, Johan A., Paul, Maarten W., Carofiglio, Fabrizia, de Gruiter, H. Martijn, Vergroesen, Tessa, Koornneef, Lieke, van Cappellen, Wiggert A., Houtsmuller, Adriaan B., Baarends, Willy M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310863/
https://ncbi.nlm.nih.gov/pubmed/32502153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008595
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