ATP-dependent and independent functions of Rad54 in genome maintenance

Rad54, a member of the SWI/SNF protein family of DNA-dependent ATPases, repairs DNA double-strand breaks (DSBs) through homologous recombination. Here we demonstrate that Rad54 is required for the timely accumulation of the homologous recombination proteins Rad51 and Brca2 at DSBs. Because replicati...

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Detalhes bibliográficos
Main Authors: Agarwal, Sheba, van Cappellen, Wiggert A., Guénolé, Aude, Eppink, Berina, Linsen, Sam E.V., Meijering, Erik, Houtsmuller, Adriaan, Kanaar, Roland, Essers, Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051825/
https://ncbi.nlm.nih.gov/pubmed/21357745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201011025
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