A novel action mechanism for MPT0G013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through up-regulation of TIMP3 expression

Tissue inhibitors of metalloproteinases 3 (TIMP3) were originally characterized as inhibitors of matrix metalloproteinases (MMPs), acting as potent antiangiogenic proteins. In this study, we demonstrated that the arylsulfonamide derivative MPT0G013 has potent antiangiogenic activities in vitro and i...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Wang, Chih-Ya, Liou, Jing-Ping, Tsai, An-Chi, Lai, Mei-Jung, Liu, Yi-Min, Lee, Hsueh-Yun, Wang, Jing-Chi, Pan, Shiow-Lin, Teng, Che-Ming
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2014
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259441/
https://ncbi.nlm.nih.gov/pubmed/25226613
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