Anticancer Activity of MPT0E028, a Novel Potent Histone Deacetylase Inhibitor, in Human Colorectal Cancer HCT116 Cells In Vitro and In Vivo

Recently, histone deacetylase (HDAC) inhibitors have emerged as a promising class of drugs for treatment of cancers, especially subcutaneous T-cell lymphoma. In this study, we demonstrated that MPT0E028, a novel N-hydroxyacrylamide-derived HDAC inhibitor, inhibited human colorectal cancer HCT116 cel...

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Detalhes bibliográficos
Main Authors: Huang, Han-Lin, Lee, Hsueh-Yun, Tsai, An-Chi, Peng, Chieh-Yu, Lai, Mei-Jung, Wang, Jing-Chi, Pan, Shiow-Lin, Teng, Che-Ming, Liou, Jing-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425516/
https://ncbi.nlm.nih.gov/pubmed/22928010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043645
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