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Synergistic Interaction between the HDAC Inhibitor, MPT0E028, and Sorafenib in Liver Cancer Cells In Vitro and In Vivo

PURPOSE: To investigate the antitumor activities of a histone deacetylase (HDAC) inhibitor, MPT0E028, plus sorafenib in liver cancer cells in vitro and in vivo. EXPERIMENTAL DESIGN: Different liver cancer cell lines were exposed to sorafenib in the presence or absence of MPT0E028, and cell viability...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Chen, Chun-Han, Chen, Mei-Chuan, Wang, Jing-Chi, Tsai, An-Chi, Chen, Ching-Shih, Liou, Jing-Ping, Pan, Shiow-Lin, Teng, Che-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284945/
https://ncbi.nlm.nih.gov/pubmed/24520095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3909
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