The HDAC inhibitor, MPT0E028, enhances erlotinib-induced cell death in EGFR-TKI-resistant NSCLC cells

Epidermal growth factor receptor (EGFR), which promotes cell survival and division, is found at abnormally high levels on the surface of many cancer cell types, including many cases of non-small cell lung cancer. Erlotinib (Tarceva), an oral small-molecule tyrosine kinase inhibitor, is a so-called t...

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Detalhes bibliográficos
Main Authors: Chen, M-C, Chen, C-H, Wang, J-C, Tsai, A-C, Liou, J-P, Pan, S-L, Teng, C-M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789188/
https://ncbi.nlm.nih.gov/pubmed/24052078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.330
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