In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells

BACKGROUND AND PURPOSE: The purpose of the current study was to assess a novel anti-cancer drug, MPT0B014, which is not a substrate for the P-glycoprotein (P-gp) transporter, alone and in combination with erlotinib, against human non-small cell lung cancer (NSCLC). EXPERIMENTAL APPROACH: Cytotoxicit...

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Detalhes bibliográficos
Main Authors: Tsai, An-Chi, Pai, Hui-Chen, Wang, Chih-Ya, Liou, Jing-Ping, Teng, Che-Ming, Wang, Jing-Chi, Pan, Shiow-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874701/
https://ncbi.nlm.nih.gov/pubmed/24116948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12427
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