A novel action mechanism for MPT0G013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through up-regulation of TIMP3 expression

Tissue inhibitors of metalloproteinases 3 (TIMP3) were originally characterized as inhibitors of matrix metalloproteinases (MMPs), acting as potent antiangiogenic proteins. In this study, we demonstrated that the arylsulfonamide derivative MPT0G013 has potent antiangiogenic activities in vitro and i...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Wang, Chih-Ya, Liou, Jing-Ping, Tsai, An-Chi, Lai, Mei-Jung, Liu, Yi-Min, Lee, Hsueh-Yun, Wang, Jing-Chi, Pan, Shiow-Lin, Teng, Che-Ming
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2014
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259441/
https://ncbi.nlm.nih.gov/pubmed/25226613
תגים: הוספת תג
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