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Diaphragm dysfunction caused by sphingomyelinase requires the p47(phox) subunit of NADPH oxidase
Sphingomyelinase (SMase) activity is elevated in inflammatory states and may contribute to muscle weakness in these conditions. Exogenous SMase depresses muscle force in an oxidant-dependent manner. However, the pathway stimulated by SMase that leads to muscle weakness is unclear. In non-muscle cell...
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| 出版年: | Respir Physiol Neurobiol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4259017/ https://ncbi.nlm.nih.gov/pubmed/25448394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2014.10.011 |
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