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NAD(P)H oxidase subunit p47(phox) is elevated, and p47(phox) knockout prevents diaphragm contractile dysfunction in heart failure
Patients with chronic heart failure (CHF) have dyspnea and exercise intolerance, which are caused in part by diaphragm abnormalities. Oxidants impair diaphragm contractile function, and CHF increases diaphragm oxidants. However, the specific source of oxidants and its relevance to diaphragm abnormal...
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| Publicat a: | Am J Physiol Lung Cell Mol Physiol |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4556931/ https://ncbi.nlm.nih.gov/pubmed/26209274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00176.2015 |
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