The Extracellular Adherence Protein from Staphylococcus aureus Inhibits the Classical and Lectin Pathways of Complement by Blocking Formation of the C3 Pro-Convertase

The pathogenic bacterium Staphylococcus aureus actively evades many aspects of human innate immunity by expressing a series of small inhibitory proteins. A number of these proteins inhibit the complement system, which labels bacteria for phagocytosis and generates inflammatory chemoattractants. Whil...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Woehl, Jordan L., Stapels, Daphne A.C., Garcia, Brandon L., Ramyar, Kasra X., Keightley, Andrew, Ruyken, Maartje, Syriga, Maria, Sfyroera, Georgia, Weber, Alexander B., Zolkiewski, Michal, Ricklin, Daniel, Lambris, John D., Rooijakkers, Suzan H.M., Geisbrecht, Brian V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258549/
https://ncbi.nlm.nih.gov/pubmed/25381436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401600
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