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The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein
The extracellular adherence protein (Eap) plays a crucial role in pathogenesis and survival of Staphylococcus aureus by inhibiting the classical and lectin pathways of complement. We have previously shown that Eap binds with nanomolar affinity to complement C4b and disrupts the initial interaction b...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5521547/ https://ncbi.nlm.nih.gov/pubmed/28512867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3195 |
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