The Neurotensin–HIF-1α–VEGFα Axis Orchestrates Hypoxia, Colonic Inflammation, and Intestinal Angiogenesis

The expression of neurotensin (NT) and its receptor (NTR1) is up-regulated in experimental colitis and inflammatory bowel disease; NT/NTR1 interactions regulate gut inflammation. During active inflammation, metabolic shifts toward hypoxia lead to the activation of hypoxia-inducible factor (HIF)-1, w...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Bakirtzi, Kyriaki, West, Gail, Fiocchi, Claudio, Law, Ivy Ka Man, Iliopoulos, Dimitrios, Pothoulakis, Charalabos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258496/
https://ncbi.nlm.nih.gov/pubmed/25307345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.08.015
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados