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Neurotensin promotes the development of colitis and intestinal angiogenesis via HIF-1α-miR-210 signaling
Neurotensin (NT) via its receptor 1 (NTR1) modulates development of colitis, decreases HIF-1α/PHD2 interaction, stabilizes and increases HIF-1α transcriptional activity and promotes intestinal angiogenesis. HIF-1α induces miR-210 expression while miR-210 is strongly up-regulated in response to NT in...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868643/ https://ncbi.nlm.nih.gov/pubmed/27076683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501443 |
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