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NPAS1 Represses the Generation of Specific Subtypes of Cortical Interneurons

Little is known about genetic mechanisms that regulate the ratio of cortical excitatory and inhibitory neurons. We show that NPAS1 and NPAS3 transcription factors (TF) are expressed in progenitor domains of the mouse basal ganglia (subpallium, MGE and CGE). NPAS1(−/−) mutants had increased prolifera...

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Dades bibliogràfiques
Publicat a:Neuron
Autors principals: Stanco, Amelia, Pla, Ramón, Vogt, Daniel, Chen, Yiran, Mandal, Shyamali, Walker, Jamie, Hunt, Robert F., Lindtner, Susan, Erdman, Carolyn A., Pieper, Andrew A., Hamilton, Steven P., Xu, Duan, Baraban, Scott C., Rubenstein, John L. R.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258152/
https://ncbi.nlm.nih.gov/pubmed/25467980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.10.040
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