Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis

The postnatal functions of the Dlx1&2 transcription factors in cortical interneurons (CINs) are unknown. Here, using conditional Dlx1, Dlx2, and Dlx1&2 knockouts (CKOs), we defined their roles in specific CINs. The CKOs had dendritic, synaptic, and survival defects, affecting even PV(+) CINs...

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Bibliographic Details
Published in:Cereb Cortex
Main Authors: Pla, Ramon, Stanco, Amelia, Howard, MacKenzie A, Rubin, Anna N, Vogt, Daniel, Mortimer, Niall, Cobos, Inma, Potter, Gregory Brian, Lindtner, Susan, Price, James D, Nord, Alex S, Visel, Axel, Schreiner, Christoph E, Baraban, Scott C, Rowitch, David H, Rubenstein, John L R
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188538/
https://ncbi.nlm.nih.gov/pubmed/29028947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhx241
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