Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis

The postnatal functions of the Dlx1&2 transcription factors in cortical interneurons (CINs) are unknown. Here, using conditional Dlx1, Dlx2, and Dlx1&2 knockouts (CKOs), we defined their roles in specific CINs. The CKOs had dendritic, synaptic, and survival defects, affecting even PV(+) CINs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cereb Cortex
Egile Nagusiak: Pla, Ramon, Stanco, Amelia, Howard, MacKenzie A, Rubin, Anna N, Vogt, Daniel, Mortimer, Niall, Cobos, Inma, Potter, Gregory Brian, Lindtner, Susan, Price, James D, Nord, Alex S, Visel, Axel, Schreiner, Christoph E, Baraban, Scott C, Rowitch, David H, Rubenstein, John L R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188538/
https://ncbi.nlm.nih.gov/pubmed/29028947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhx241
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