Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis

The postnatal functions of the Dlx1&2 transcription factors in cortical interneurons (CINs) are unknown. Here, using conditional Dlx1, Dlx2, and Dlx1&2 knockouts (CKOs), we defined their roles in specific CINs. The CKOs had dendritic, synaptic, and survival defects, affecting even PV(+) CINs...

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Detalhes bibliográficos
Publicado no:Cereb Cortex
Principais autores: Pla, Ramon, Stanco, Amelia, Howard, MacKenzie A, Rubin, Anna N, Vogt, Daniel, Mortimer, Niall, Cobos, Inma, Potter, Gregory Brian, Lindtner, Susan, Price, James D, Nord, Alex S, Visel, Axel, Schreiner, Christoph E, Baraban, Scott C, Rowitch, David H, Rubenstein, John L R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188538/
https://ncbi.nlm.nih.gov/pubmed/29028947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhx241
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