NPAS1 Represses the Generation of Specific Subtypes of Cortical Interneurons

Little is known about genetic mechanisms that regulate the ratio of cortical excitatory and inhibitory neurons. We show that NPAS1 and NPAS3 transcription factors (TF) are expressed in progenitor domains of the mouse basal ganglia (subpallium, MGE and CGE). NPAS1(−/−) mutants had increased prolifera...

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Udgivet i:Neuron
Main Authors: Stanco, Amelia, Pla, Ramón, Vogt, Daniel, Chen, Yiran, Mandal, Shyamali, Walker, Jamie, Hunt, Robert F., Lindtner, Susan, Erdman, Carolyn A., Pieper, Andrew A., Hamilton, Steven P., Xu, Duan, Baraban, Scott C., Rubenstein, John L. R.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258152/
https://ncbi.nlm.nih.gov/pubmed/25467980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.10.040
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